Science

Exploring the Allosteric Modulation
of Organelle Specific Molecular Chaperones

Cellular Stress
Cellular Stress
Molecular chaperones are well known as mediators of protein folding, but they also serve as physiological sensors that respond to changes in electrolyte levels and metabolism to maintain cellular homeostasis. Through the development of small-molecule activators of organelle-specific chaperones, Amathus Therapeutics aims to enhance the broad protective capacity of these homeostatic regulators, particularly in diseases driven by deficits in chaperone activity.

Cellular Stress Response Involves
Organelle-Specific Chaperones

Cellular Stress Response
Cellular Stress Response